Detail from a View of the West Front of Monticello and Garden by Jane Braddick Peticolas.

Mary was born in 1803. Her mother was Martha Jefferson Randolph. Her father was Thomas Mann Randolph. She was born at Edgehill, her parent’s plantation. She spent much of her time at Monticello.

Mary never married. With her sister, Cornelia, she opened a ladies school at Edgehill. She also helped nurse her nieces and nephews. After the Civil War, Mary lived with two of her sisters. She died in 1876.